Apps – Mutagenic Impurity Analysis

Mutagenic Impurity Analysis

The BrightSpec Solution

Mutagenic impurities pose a significant challenge for pharamaceutical analytical chemists, given that they are a health risk even at trace levels. Identification and quantitation of these (often unknown) impurities can be an onerous process. MRR provides fingerprint spectra of impurities based on the three-dimensional moments of inertia, and can be identified through comparison to BrightSpec’s spectral library, or even directly to quantum chemical calculations without a reference standard required. BrightSpec has developed a Thermal Evolution sampling method to release all volatile impurities in a solid sample, which delivers structural identification and quantitation in one measurement. This can dramatically speed up the impurities characterization and improve process control.

Structural identification and quantitation in one measurement speeds up the impurities characterization